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The PlA1/PlA2 polymorphism lies in the gene to the β3 (GPIIIa) subunit of αIIbβ3 (GPIIb-IIIa). This integrin serves being a receptor for adhesive proteins fibrinogen and von Willebrand issue which is vital for that cohesive Attributes of platelets. Recognition of those proteins as soluble ligands involves αIIbβthree to generally be activated b